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15. WinClean
You can bookmark any key in the Registry and access the registry key with a single mouse click. So you can create a set of Registry keys that you frequently access eliminating the need to manually open Regedit.
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Platform: Windows 95, Windows NT, Windows 2000, Windows XP, Windows 98, Windows ME
Vendor: Chandra Lesmana

16. WinASO Registry Optimizer

WinASO Registry Optimizer is an advanced registry cleaner and optimizer for Windows that allows you to safely clean and repair registry problems with a few simple mouse clicks. WinASO Registry Optimizer can restoring Internet Explorer setting, including IE Home Page, IE Window Title, etc. Version 2.0 adds more features, includes: Repair Internet Explorer, Speed-up your System, System Tools, etc. Unlimited free upgrades and e-mail technical support for one year.

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Platform: Windows NT, Windows 2000, Windows XP, Windows 98, Windows ME, Win98/ME/NT/Windows2000/WinXP
Vendor: X.M.Y. International LLC

17. MyMappeR
This is mapped tcp port for LAN/Internet users with firewall. It doesn't require installation and will not add new registry keys at Windows registry database at first use.
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Platform: Windows 3.1x, Windows 95, Windows 2000, Windows XP, Windows 98, Windows ME
Vendor: Nickolay Asenov

19. KLS Backup 2005 Professional
KLS Backup 2005 Professional is a powerfull backup software for Windows, designed to backup any type of data (local files and folders, network locations, FTP servers, registry keys, MySQL databases, application profiles and windows settings).
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Platform: Windows 95, Windows NT, Windows 2000, Windows XP, Windows 98, Windows ME, Windows Server 2003
Vendor: KLS Soft

20. WinTools.net Classic
Scan Registry - This tool is used for periodic cleaning of the MS Windows registry from unused applications remained after uninstallation and from invalid references which decrease system speed and system loading time. WinTools.net cleanly removes unwanted software from disk drives and dead references from the Windows registry.
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Platform: Windows 95, Windows 2000, Windows XP, Windows 98, Windows ME
Language: English, German
Vendor: WinTools Software Engineering, Ltd.

21. Advance System Optimizer

ASOv2 includes 30+ tools to supercharge your PC's performance, and more than 200 tweaks to customize Windows to your liking, and improve its performance. Registry cleaner ensure that invalid information is removed. Registry defragger help you get maximum speed from your computer.

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Platform: Windows NT, Windows 2000, Windows XP, Windows 98
Vendor: Systweak

22. Software-Promoter
Software-Promoter does two things for you: it processes all incoming registration orders from your customers, maintains it, generates registration keys, sends letters and helps you to promote your software. External key generators and AsProtect are supported.
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Platform: Windows 95, Windows NT, Windows 2000, Windows XP, Windows 98, Windows ME, Internet Explorer 5
Vendor: Nick Mokhnatov, Independent software developer

23. inDesign Virus Detector 1.0.2004

It has two parts: VDetector and VMonitor How does it work: VDetector creates file information database of files with extensions default (exe; dll; com; ocx; vbs; vtx; xml; xsl; vsc) from Windows directory and from other directories in your computer that you choose manually and it detects: - File size changes - New Files - Deleted files It also detects registry changes: - New values - Deleted values in Windows startup keys and from other keys that you choose manually.

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Platform: Windows NT, Windows XP, Windows 98, Windows ME
Vendor: InCode Solutions

24. WinTools.net Professional

Scan Registry - This tool is used for periodic cleaning of the MS Windows registry from unused applications remained after uninstallation and from invalid references which decrease system speed and system loading time. WinTools.net Professional contains tools: Clean Uninstaller, Scan Files, Scan Registry, Start Up, Tweak UI, Net Tweaker, The Privacy... Clean Uninstaller - This tool is used for both correctly removing software and for monitoring changes made to the hard drive, MS Windows registry and system files during program installations.

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Platform: Windows 95, Windows NT, Windows 2000, Windows XP, Windows 98, Windows ME
Language: English, German
Vendor: WinTools Software Engineering, Ltd.

25. Ace Optimizer Utilities
Other features include secure file deletion, disk space analysis, tweaking of hidden settings, an Empty Folder finder and more. Furthermore, Ace Utilities includes options to find true duplicate files, fix or remove broken shortcuts and to uninstall software.
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Platform: Windows 2000, Windows XP, Windows 98, Windows ME, Windows Server 2003
Vendor: AceLogiX